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1.2.09

Management of Ageing Processes in Graphite Reactor Cores

Publisher: Royal Society of Chemistry
Language: English
ISBN: 0854043454
Paperback: 300 pages
Data: Jul 2007
Format: PDF
Description: Many nuclear reactors and components are coming to the end of their ‘useful’ life and strategies for the effective management of these decommissioned parts are paramount. Management of Ageing Processes in Graphite Reactor Cores discusses in detail both the scientific challenges and the issues involved in this subject. Covering fundamentals of reactor design through to graphite-component behaviour and its assessment, the book also provides a discussion of the lessons learnt from decades of experience. Written by leading experts in the field, this is an ideal resource for both academia and industry, and is of great relevance to policy makers and governments.
http://rapidshare.com/files/188387374/0854043454.rar

21.12.08

Molecular Biology Methods eBooks Download

20.12.08

ebook Biomechanics at Micro- and Nanoscale Levels Volume IV

World Scientific Publishing Company | 2007-09-24 | ISBN: 981277131X | 180 pages | PDF | 10,3 MB

A project on Biomechanics at Micro- and Nanoscale Levels , the title of this book, was approved by the Ministry of Education, Culture, Sports, Science and Technology of Japan in 2003. This 4-year-project was carried out by 14 prominent Japanese researchers and ended in late March 2007. The project consisted of four fields of research, namely, cell mechanics, cell response to mechanical stimulation, tissue engineering, and computational biomechanics.
A series of four books related to this project was published between 2003 and 2007. The present volume is the last book in this series, and summarizes the research results achieved by project members throughout its 4-year duration. This book is essential reading for those interested in understanding current trends of research in the area of biomechanics at micro- and nanoscale levels.

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ebook Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists

Springer | 2008-12-11 | ISBN: 1848002548 | 274 pages | PDF | 19,4 MB

The major difficulty many microbiologists face is simply that of too much information. As a result of sequencing technologies becoming so economical, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes.
This accessible text/reference provides a coherent set of tools and a methodological framework for comparing raw DNA sequences and fully annotated genome sequences, then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Easy-to-follow, this introductory textbook is built around teaching computational / bioinformatics methods for comparison of microbial genomes, and includes detailed examples of how to compare them at the level of DNA, RNA, and protein, in terms of structural and functional analysis.
Topics and Features:
• Contains five introductory chapters each representing a specific scientific field, to bring all readers up to the same basic level
• Familiarizes readers with genome sequences, RNA sequences (transcriptomics), proteomics and regulation of gene expression
• Describes basic methods to compare genomes and visualize the results for easy interpretation
• Discusses microbial communities, providing a framework for analysing and comparing individual genomes or raw DNA derived from complete ecosystems
• Introduces various atlases, building up to the Genome Atlas
• Offers numerous helpful examples throughout
• Focuses on the use and interpretation of publicly available Web tools
• Provides supplemental resources, such as Web links, at http://comparativemicrobial.com
Developed from a set of lectures for a course in Comparative Microbial Genomics taught since 2001, this wide-ranging foundational textbook is aimed at advanced undergraduate and graduate students in Bioinformatics and Microbiology. The authors are from diverse backgrounds complementing the interdisciplinary nature of the topic and consequently have developed a common scientific language. Readers will find this text an invaluable reference for computational and bioinformatics tools.

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Download ebook Fundamentals of Cryobiology: Physical Phenomena and Mathematical Models

Springer | 2009-01-01 | ISBN: 3540887849 | 278 pages | PDF | 2,7 MB

The book gives a summary of the state of the art of cryobiology and its applications. The accent is on the underlying physical phenomena, which are common in such opposite applications as cryosurgery and cryoconservation, and the corresponding mathematical models, including numerical ones. The treatment of some more special issues is moved to the appendices. The glossary contains definitions and explanations of the major entities. All the topics considered are well referenced. The book is useful to both biologists and physicists of different level including practitioners and graduate students.

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Advances in Haploid Production in Higher Plants ebook

Springer | 2008-12-05 | ISBN: 1402088531 | 348 pages | PDF | 12,8 MB

The discovery of haploid Datura plants in 1964 initiated great excitement in plant breeding and genetics communities. Recent years have witnessed a resurgence in activities especially in developing protocols, identifying genes and mechanisms and large scale commercial take up.

The identification of controlling genes has driven functional genomic studies which now link in with studies in gene expression, metabolism and changes in cell ultra-structure. World wide take up by plant breeders has been no less impressive and valuable haploid technologies is increasingly patent protected. The intense activity in haploid research has also resulted in unexpected findings with novel applications.

The core of this book is based on the international symposium on "Haploidy in Higher Plants III", (Vienna 2006), which attracted top international experts in the field. Other invited contributions have been included to provide a rounded view of activities.

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19.12.08

Gene Avatars: The Neo-Darwinian Theory of Evolution

Product Description

`Why life?' Questions of this type were for a long time the prerogative of philosophers who left the `how' question to scientists. Nowadays, Darwin's successors no longer have any qualms about addressing the `why' as well as the `how'. Over a century ago, Darwin modestly admitted having 'thrown some light on the origin of species - this mystery of mysteries'. Two major advances in the following decades helped biologists answer many of the questions he left unsolved. The first was the discovery of the laws of heredity, the second that of DNA. Both provided Darwinian theory with the foundations that were lacking and led to the all-embracing neo-Darwinian synthesis. Since then, Theodosius Dobzhansky's aphorism `nothing in biology makes sense except in the light of evolution' has proven true more than once. This does not suit everyone, as evolutionist ideas have not lost their power to cause a scandal.

Darwin toppled man from his pedestal. Evolutionary genetics - the subject of this book - sends the individual crashing. Considered until recently to be the target of selection and the focus of evolution, the individual has been usurped by the gene. The individual is nothing but the gene's avatar

http://rapidshare.com/files/174625950/Gouyon__Henry__Arnould._Gene_avatars.._the_neo-Darwinian_theory_of_evolution__Kluwer_2002__ISBN_0.pd

18.12.08

Coupled Bioluminescent Assays: Methods, Evaluations, and Applications

Product Description
This book highlights the applications of coupled bioluminescence assay techniques to real-world problems in drug discovery, environmental and chemical analysis, and biodefense. It separates theoretical aspects from the applied sections in a clear and readable way. Coupled Bioluminescent Assays, explains the uses of CB technologies across drug discovery to analyze toxicity, drug receptors, and enzymes. It covers applications in environmental analysis and biodefense, including cytotoxicity, fertilizer and explosives analysis, and nerve agent and pesticide detection. This is the premier reference on coupled bioluminescent assays for chemists, biochemists, and molecular biologists.
Product Details

* Hardcover: 312 pages
* Publisher: Wiley (November 24, 2008)
* Language: English
* ISBN-10: 0470108835
* ISBN-13: 978-0470108833

http://rapidshare.com/files/157460594/0470108835_CoupledBio.rar

Immunology at a Glance 7th ed

Immunology at a Glance provides a concise, and accessible introduction and revision aid for undergraduate medical and science students. Following the familiar, easy-to-use at a Glance format, each topic is presented as a double-page spread with key facts accompanied by clear, informative line diagrams illustrating the essential points.

Immunology at a Glance will continue to appeal to all students of biomedical science and medicine who want a quick, yet thorough grasp of immunology.

http://rapidshare.com/files/166899810/Immunology_at_a_Glance_7th_ed.pdf

Plant (DK Eye Wonder)

From carniverous leaves to the magic of pollination, plants are vital to life on earth. Packed with fun facts and dramatic photography, Eye Wonder Plants is great for projects and homework or just for fun.

Examine what a plant is, find out how plants support all other life on the planet, and discover their tricks of attracting pollinators and the secret weapons they use to keep predators at bay.

http://rapidshare.com/files/166928483/F36E2165-146C-4946-A86E-E2E6C4978E3C.rar

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25.11.08

ebook-Echocardiography Board Review: 400 Multiple Choice Questions With Discussion (2008)

Description: Obtaining an echocardiogram is a complex procedure with a need for constant enhancement and improvement of skills in the area for both ultrasound technician and physician.A^ Owing to the increasing complexity of the echocardiogram and its interpretation, upon which patient care heavily relies, various professional bodies have been introducing competency exams.

This unique book has been designed to assist new trainees as well as more experienced technicians and physicians in preparing for competency exams for certification purposes. It provides easy-to-use revision material in the form of multiple-choice questions with clearly explained answers.

* Unique approach to echocardiography in a question and answer format; the questions are predominantly case studies
* Features 400 questions with answers and explanations. The scope of the questions in the book is broad, including areas such as applied ultrasound physics, haemodynamics, valvular problems, ischaemic heart disease, congenital heart diseases, intraoperative or surgical echocardiography, pericardial diseases and cardiac masses.
* Excellent for test preparation
* Easy to read and understand
* Complements standard textbook reading
* Written by experienced academic echocardiographers involved in teaching echocardiography every day
* Over 200 still images enhance the learning process

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28.3.08

Ebook New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions

New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions
Author: Gertz I. Likhtenshtein

Publisher: Springer
Publication Date: 2002-12-31
Number Of Pages: 240
# ISBN-10: 1402010060
# ISBN-13: 978-1402010064
Book Description

New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions embraces modern areas of enzyme catalysis where other books in the field concentrate mainly on kinetic, bioorganic and biochemical aspects of the enzyme catalysis and do not cover biophysical and physicochemical problems. Topics covered include:

-modern physical and kinetic methods of investigation,
-contemporary theories of elementary chemical processes in enzymes,
-structure, dynamics and action mechanism of enzyme active sites,
-concept of pretransition state,
-theory of long-range electron transfer and proton translocation,
-mechanisms of "tough" biochemical reactions (dinitrogen reduction, light energy conversation, water photooxidation, hydroxilation),
-the achievements and problems of biomimetic chemical reactions.

Table of Contents

Preface
Ch. 1Methods of investigation of enzymes structure and action mechanisms1
Ch. 2Mechanisms of enzymatic reactions35
Ch. 3Mechanisms of chosen enzyme systems81
Ch. 4Some properties important for enzyme catalysis132
Ch. 5Areas related to enzyme catalysis164
Ch. 6Model chemical systems172
References189
Index228

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9.3.08

Book For Protein Structure Prediction (Methods in Molecular Biology)

Product Details
»Book Publisher: Humana Press (12 September, 2007)
»ISBN: 1588297527
»Book author: Mohammed Zaki, Chris Bystroff
»Amazon Rating:

Book Description:

This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules, such as small ligands, nucleic acids or other proteins. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure. This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners.

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Book For Microtubule Protocols (Methods in Molecular Medicine)

Product Details
»Book Publisher: Humana Press (23 August, 2007)
»ISBN: 1588296423
»Book author: Jun Zhou
»Amazon Rating:

Book Description:

Microtubules are essential components of the cytoskeleton, and play critical roles in a variety of cell processes, including cell shaping, intracellular tracking, cell division, and cell migration. Microtubule Protocols presents a comprehensive collection of essential and up-to-date methods for studying both the biology of microtubules and the mechanisms of action of microtubule-interacting drugs. The straightforward presentation of readily reproducible protocols is a hallmark of the Methods in Molecular Medicine series, and is evident in this volume. Methods presented range from the purification and characterization of microtubule proteins, analysis of post-translational modifications of tubulin, and determination of microtubule structure, to the visualization of microtubule and spindle behavior, measurement of microtubule dynamics, and examination of microtubule-mediated cellular processes. Both basic scientists and clinical researchers will benefit from this collection of state-of-the-art protocols for microtubule research.

Length:3.2 MB
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Book-Neuroprotection Methods and Protocols (Methods in Molecular Biology)

Product Details
»Book Publisher: Humana Press (08 August, 2007)
»ISBN: 1588296660
»Book author: Tiziana Borsello
»Amazon Rating:

Book Description:

This book examines current research and methods into neuronal death signaling pathways, with the main aim of providing an overview of methods used to study neuronal death and neuroprotection and offering a truly comprehensive, step-by-step guide that makes clear not just the procedure but also the principles behind the use of it.

Length:2.2 MB
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Book International Review Of Cytology, Volume 261: A Survey of Cell Biology (International Review of Cytology) (International Review of Cytology)

Product Details
»Book Publisher: Academic Press (18 June, 2007)
»ISBN: 0123741602
»Book author: Kwang W. Jeon
»Amazon Rating:

Book Description:
International Review of Cytology presents current advances and comprehensive reviews in cell biology both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume include LEM-domain Proteins: New Insights into lamin-interacting Proteins; New Insights into Membrane Trafficking and Protein Sorting; Structure and Function of the Atypical Orphan Nuclear Receptor; Zebrafish Gastrulation: Cell Movements, Signals and Mechanisms; Calcium Dynamics: Spatio-tempral Organization from the Subcellular to the Organ Level; New Technologies Used in the Study of Human Melanoma.

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Download G Proteins, Cytoskeleton and Cancer (Molecular Biology Intelligence Unit)

Product Details
»Book Publisher: LANDES BIOSCIENCE PUBLISHERS (01 October, 1998)
»ISBN: 1570595518
»Book author: Hiroshi, Ed. Maruta
»Amazon Rating: 3.0

Book Description:
This book is about the role of G protein-mediated signal transduction–Ras, Rho, gelsolin, et cetera–and the cytoskeleton in carcinogenesis. 377 pages, 72 figures, 9 tables, hardcover

http://www.filefactory.com/file/6178ae/

Book Pathology of Laboratory Rodents and Rabbits, Third Edition

Product Details
»Book Publisher: Wiley-Blackwell (08 February, 2008)
»ISBN: 0813821010
»Book author: Dean H. Percy, Stephen W. Barthold
»Amazon Rating:

Book Description:
Pathology of Laboratory Rodents and Rabbits has become a standard text for both veterinary pathologists and veterinarians in laboratory animal medicine. Newly recognized infectious diseases continue to emerge and molecular methods for studying infectious agents are becoming widely used for the classification of these and previously known pathogens. With the ongoing development and perfection of genetic engineering techniques, the use of genetically engineered mice in the research laboratory continues to grow exponentially.

This new edition features updates throughout with increased emphasis on timely topics such as infectious diseases in genetically engineered mice. Diseases covered include viral infections, bacterial infections, parasitic diseases, nutritional and metabolic disorders, behavioral disorders, aging and degenerative disorders, environment-related disease, and neoplasms. Organized by species, coverage includes mice, rats, hamsters, gerbils, guinea pigs, and rabbits. Veterinary pathologists, laboratory animal veterinarians, and students will appreciate the concise organization and easily accessible information on key diagnostic features, differential diagnoses, and significance of diseases.

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Download Bacterial Biofilms (Current Topics in Microbiology and Immunology)

Product Details
»Book Publisher: Springer (April, 2008)
»ISBN: 3540754172
»Book author: Tony Romeo
»Amazon Rating:

Book Description:

Throughout the biological world, bacteria thrive predominantly in surface attached, matrix enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections.

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Download Handbook of Models for Human Aging

Product Details
»Book Publisher: Academic Press (24 February, 2006)
»ISBN: 0123693918
»Book author: P. Michael Conn
»Amazon Rating:

Book Description:
This Handbook is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer’s to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues.

*Utilizes a multidisciplinary approach
*Shows tricks and approaches not available in primary publications
*First volume of its kind to combine both methods of study for human aging and animal models
*Over 200 illustrations

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